University of Southern California

The Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research

Architecture/Engineering integration optimized with CFD.

While the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research reduces energy consumption by 30 percent through use of chilled beams alone, this Laboratory of the Year honoree perhaps most prominently demonstrates the successful realization of a design concept integrated with optimal envelope and mechanical system performance. AEI provided CFD energy performance and daylight analyses allowing the double skin façade air cavity ventilation to reduce heat gain in warm temperatures and create an insulating layer when it’s cool.


Los Angeles, CA


  • ZGF Architects - Architect of Record

LEED Status


Building Size

87,500 square feet


  • 2012 Architectural Award - Sustainability Category
  • 2012 Calibre Award
  • 2011 Sustainable Innovation Award
  • 2011 High Honors Laboratory of the Year Award

Open labs are flanked by support spaces for fume hoods and tissue/cell culture rooms.

Associated with USC’s Keck School of Medicine, the Broad Center was created to be a magnet for biotechnical talent focused on developing life-saving cures through collaborative stem cell research across disciplines. Teams focus on ophthalmology, gastroenterology, cardiovascular medicine, hematology, and oncology, recognized worldwide as areas of clinical research excellence for USC. The building is connected to the adjacent Zilkha Neurogenic Institute and houses the Stem Cell Collaborative and Training Core, part of the California Institute for Regenerative Medicine

large-scale lab use of chilled beams in California.

Angled glass fins reduce glare without blocking exterior views. Photocells reduce the electric lighting levels when adequate daylight is available.

East and west sides of the building have glass facades running the full length to maximize natural lighting in the labs and offices. West has Low-E glass with a frit pattern to reduce heat gain.

LEED Gold USC Health Sciences building.

Project Leaders